If your looking for a tourist type place then Edinburgh would be were you want to go as it has the castle, dungeons and all the tourists kind of shops.

If your not looking for the tourist scene then Glasgow is the better option as it has great retail shops, and the nightlife is amazing. It also has the Kelvingrove museum and botanic gardens, which are really good.

Both places have lots of history and lots of things to see.
P.S Prestwick is no were near Glasgow.

Hotels in Edinburgh, forget if unless you are rich. Try a BB (Bed and Breakfast).

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Glasgow wouldn’t the second most visited place in the UK after London if what the bitter people above said was true.

Glasgow, the largest city in Scotland, offers fabulous shopping, crowded pubs and clubs and terrific restaurants. Art lovers will also find plenty to capture their imagination, as the city is home to more than 30 galleries and museums, including the world famous Burrell Collection and Saint Mungo Museum of Religious Life and Art.

Naturally it is also possible to visit the coast from Glasgow or discover the rich history of the region by exploring neighbouring cities and villages.

Architecture: Many of the city’s buildings date back to the 19th century, when Glasgow was the trading centre of Scotland. Nowadays, the city palaces of yesteryear serve as offices and department stores.

Enjoying both architecture and the contents of the buildings is the theme of The Lighthouse in the heart of Glasgow, with a variety of dynamic exhibitions on art and architecture.

Shopping: Glasgow is the largest shopping city of Great Britain after London and offers excellent shopping. Visit the pedestrianised shopping precincts Sauchiehall Street, Buchanan Street and Argyle Street or one of the indoor shopping malls, such as the Buchanan Galleries or St Enoch Centre.

Food and drink: Whisky, preferably single malt, is the drink of choice in Scotland. A visit to a distillery is certainly worthwhile.

Like in England, the Scots enjoy a hearty breakfast with bacon and eggs, whereas dinner usually consists of a wide selection of meats. Salmon is also widely available. Mutton lovers must certainly try the traditional Haggis.

Getting Around: Glasgow has one of the most advanced, fully integrated public transport systems in Europe. Glaswegians are very reliant on buses, the underground, and the local railway network that cross the city and link it to the suburbs. The Travel Centre at St Enoch Square (+44 (0) 141 226 4826) is a good starting-point for general Glasgow-wide travel information.

Underground: The Glasgow Underground has twin tunnels providing a circular service linking 15 stations. Trains are frequent (approximately one every five minutes), and tickets are cheap, but must be bought in advance of the journey either from a machine or from the ticket office at the station.

Rail: An extensive network of regular and frequent local rail services operates in Glasgow, its suburbs and the West of Scotland. Most suburbs and towns within this area are accessible by train. If you are staying outside Glasgow and do not want to drive into the city, you can use the 'Park-and-Ride' system, which allows free parking at suburban rail stations, where you then continue your journey by train. CCTV protects most of the parking facilities - the Park-and-Ride also operates at four Glasgow Underground stations.

EDIT:
To the people who say Prestwick isn’t a Glasgow airport, you clearly don’t know anything about the airline industry! Its easier to get from Glasgow Prestwick Airport to the centre of Glasgow than it is from all five London airports to the centre of London. So if Glasgow Prestwick is not a Glasgow airport, then London doesn’t have any airports!

The train from Glasgow Prestwick Airport to Glasgow Central takes 30 minutes, try getting from Heathrow, Gatwick, Stansted and the others to central London in 30 minutes!